| dc.description.abstract | The Proximate composition, phytochemical composition and the effect of oral administration of aqueous
extract of Terminalia schimperiana root on male wistar rat sexual behavior were determined. The root
was collected and extracted with water, the phytochemical screening was carried out using the standard
procedures and revealed the presence of alkaloids, saponins, Phenolics, anthocyanin and Tannins. The
Proximate analysis results obtained showed the amount of crude protein, crude fat and total
carbohydrates to be 6.31±0.75, 4.64±0.82 and 17.79 ±0.53 respectively of the sample while the
percentage of crude fiber, ash and moisture content in the root sample were 32.72 ±0.59, 0.35±0.12 and
10.35±0.18 respectively. Aqueous extract of Terminalia schimperiana root was orally administered to
sexually active rats in a daily dose of 1000, 2000 and 3000 mg/Kg body weight for 5 days, the sexual
behavior was monitored and testosterone serum level was measured on Terminalia schimperiana treated
rats, control rats “that received vehicle” and the reference group “ that received Powmax”. Oral
administration of Terminalia schimperiana significantly increased the mount frequency, intromission
frequency and prolonged the ejaculatory latency. In addition, a significant increase in the copulatory
efficacy was reported for the test groups and testosterone serum level was significantly increased in
Terminalia schimperiana treated rats compared to controls and reference. The present study revealed that
continuous administration of Terminalia schimperiana aqueous extract for a period of 5 days improves
the sexual motivation and performance in adult male rats, an effect that may be linked to increased
testosterone level, the nutrient composition and the phytochemicals. | en_US |
