Browsing Research Papers by Issue Date
Now showing items 1-20 of 43
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Malariometric indices from Iganga, Uganda: baseline characterization in preparation of GMZ2 vaccine trial
(2014)Background: Malaria still remains the leading cause of childhood morbidity and mortality in Uganda. Interventions like malaria vaccines which reduce the malaria burden are needed in malaria endemic communities. There is ... -
Prevalence of glucose-6-phosphate dehydrogenase deficiency and its association with Plasmodium falciparum infection among children in Iganga distric in Uganda
(Biomed central, 2014)Background: Glucose-6-phosphate dehydrogenase (G6PD) is a metabolic enzyme involved in the pentose phosphate pathway, its especially important in red blood cell metabolism. Glucose-6-phosphate dehydrogenase deficiency is ... -
Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors that Affect Treatment Outcomes for P. falciparum Malaria after Artemether-Lumefantrine and Artesunate-Amodiaquine
(2014)Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter ( pfcrt) ... -
Parasite Specific Antibody Increase Induced by an Episode of Acute P. falciparum Uncomplicated Malaria
(2015)Introduction There is no approved vaccine for malaria, and precisely how human antibody responses to malaria parasite components and potential vaccine molecules are developed and maintained remains poorly defined. In ... -
Frequency of RANTES gene polymorphisms and their association with incidence of malaria: a longitudinal study on children in Iganga district, Uganda
(Bio Med Central, 2015)Background: The severity and outcome of malaria is influenced by host immunity in which chemokines such as Regulated upon Activation, Normal T cell Expressed and Secreted (RANTES) play an important role. Previous studies show ... -
Novel flow cytometry technique for detection of Plasmodium falciparum specific B‑cells in humans: increased levels of specific B‑cells in ongoing infection
(Malaria Journal, 2015)Background: Malaria caused by Plasmodium falciparum is still a major health threat in endemic areas especially for children below 5 years of age. While it is recognized that antibody immunity plays an important role in ... -
Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens
(2015)Background: Malaria is a major global cause of deaths and a vaccine is urgently needed. Results: We have employed the P. falciparum merozoite antigens MSP2-3D7/FC27 and AMA1, used them in ELISA, and coupled them in ... -
Individual risk factors contributing to the prevalence of teenage pregnancy among teenagers at Naguru teenage center kampala, Uganda
(Primary Healthcare: Open Access, 2016)Introduction: Teenage pregnancy and its effects on teen motherhood are among the major societal challenges of the teenagers in the contemporary global community. In a 30 million population 25 percent pregnancy rate ... -
Characterization and Antimicrobial Susceptibility Patterns of Isolates from Ward Fomites
(British Biotechnology Journal, 2016)Aim: The study was conducted to determine antimicrobial susceptibility patterns among isolates from ward fomites at Kiwoko Hospital and to detect resistances in the form of Macrolide Lincosamide StreptograminB (MLSB), ... -
The S-Gene Mutations in the Circulating HBV Genotypes/Sub-Genotypes Associated with Hepatitis B Infection in Uganda and their Effects on Cytokines Expression in Liver Disease Progression
(Global Journal of Medical Research, 2016)The causal agent for hepatitis B is called hepatitis B virus (HBV). It is a partially double stranded circular DNA virus of the family Hepadnaviridae. It has been implicated as the leading cause of hepatocellular carcinoma ... -
Characterization and Antimicrobial Susceptibility Patterns of Isolates from Ward Fomites
(British Biotechnology Journal, 2016)Aim: The study was conducted to determine antimicrobial susceptibility patterns among isolates from ward fomites at Kiwoko Hospital and to detect resistances in the form of Macrolide Lincosamide StreptograminB (MLSB), ... -
Comparative Detection of Foot-and-Mouth Disease Virus by the two Commonly used Assays of NSP ELISA and RT-PCR in Uganda with Quantitative Real Time RT-PCR on Field Samples
(Global Journal of Medical Research, 2016)Foot-and-mouth disease (FMD) is a viral disease of Ungulates; both Artiodactyla and Perissodactyla. The mortality rates are low in adult animals but it affects milk yield and international trade. In endemic countries, ... -
Sexual behavior effect of orally administered crude aqueous extract of Terminalia schimperiana Root in male Wistar rat
(Plant Journal, 2016)The Proximate composition, phytochemical composition and the effect of oral administration of aqueous extract of Terminalia schimperiana root on male wistar rat sexual behavior were determined. The root was collected and ... -
Development of Plasmodium falciparum specific naïve, atypical, memory and plasma B cells during infancy and in adults in an endemic area
(Bio Med Central, 2017)Background: B-cells are essential in immunity against malaria, but which sub-sets of B-cells specifically recognize Plasmodium falciparum and when they appear is still largely unknown. Results: Using the flow cytometry ... -
Prevalence and factors associated with low back pain among healthcare workers in kibuli Muslim hospital kampala, Uganda
(OIMICS International, 2017)Background: Low back pain was not only considered to be the most common reason for functional disability worldwide, but also estimated to have affected 90% of the universal population. This study aimed at determining ... -
Discrimination of people living with HIV/AIDS by health care students of Islamic University in Uganda
(Akamai University, 2017)In May 2016, the World Health Assembly developed the Global Health Sector Strategy on HIV for 2016–2021 which strives to ensure zero HIV related discrimination especially in health institutions and settings. The main ... -
Evaluation of Proximate Composition and Phytochemical analysis of Terminalia Schimperiana Root.
(Academia, 2017)The Proximate composition and phytochemical characteristics were determined for Terminalia schimperiana root. The root was collected and extracted with water and the phytochemical screening was carried out using the standard ... -
Histopathological and Organ-Body Weight Ratio Alterations Induced by Oral Administration of AQUEOUS Extract of Terminaliaschmiperiana Root in Some Selected Organs in Male WISTAR Rats
(International Journal of Advanced Research in Science, Engineering and Technology, 2017)The toxic potential of the crude aqueous extract was investigated by evaluating the body-weight ratioand histologic changes of the liver, kidney and testes after oral administration of the extractto rats at various doses ... -
Antioxidant activities of Hydro-ethanol and Saponin extracts of Terminalia schimeperiana root
(Der Pharmacia Lettre, 2017)In this present paper we have investigated the Antioxidant activity of Hydro-ethanol and Saponin fractions of Terminalia schimperiana root for its free radical scavenging activity by adopting ABTS and DPPH in vitro methods. ... -
Anastomosed triplicated branches of the superior cerebellar arteries: a rare case of cerebral arterial plexus
(2018)Triplications of the superior cerebellar arteries are rare cases but when present are culminating factors to thromboembolism and arterisclerosis leading to infarction of areas supplied. We present a rare case of arterial ...
